24 In the present study the mean values for foot and vertebral lengths in the dystocia group were lower. Van Bogaert showed significantly lower mean lower limb (P=0.004), vertebral (P=0.003), and foot (P=0.005) lengths in the dystocia group, which supported the results of the current study.11 In the study by Awonuga et al., foot length in the dystocia group was lower (P=0.001).25 Rozen Holc Inhibitors,research,lifescience,medical et al. reported that the mean foot length in the dystocia group was 21.4 whereas in the normal delivery group it was 22.9 cm (P≤0.001).23 Okewole et al. found no significant relationship between foot length and type of delivery (P=0.24).26 With regards
to the shorter stature of women in the dystocia group in the present study, possibly the lower mean foot and vertebral lengths could be related to the small body size of this group. As an adverse outcome of dystocia, neonates with dystocia had four times greater first minute APGAR scores <9. Tsvieli et al. reported lower mean first and fifth minute APGAR scores in the dystocia group (P≤0.001).27 A number of studies Inhibitors,research,lifescience,medical such as the study by Inhibitors,research,lifescience,medical Surapanthapisit
and Thitadilok have reported no significant relationship between APGAR score and delivery type.10 Currently researchers believe that anxiety leads to hyperactive contractions, which inhibit fetal blood supply and result in hypoxia.17 In this regard, anxiety is an important risk factor for dystocia, hence the low first minute APGAR score may have been attributed not only to a prolonged delivery but also to the mother’s anxiety. Conclusion According to the results of this study the most important risk factor for dystocia in nulliparous women were moderate Inhibitors,research,lifescience,medical to high anxiety scores, occipito-posterior fetal head position, fetal head swelling during the second phase, Michaelis sacral transverse diameter ≤9.6 cm, and height to fundal height ratio <4.7. Measuring these parameters in addition to special care
during labor and delivery in high risk women might effectively prevent Inhibitors,research,lifescience,medical dystocia and its complications. Acknowledgment This study is part of an approved research Entinostat thesis project by MUMS (No 87325).We full article express our appreciation to the MUMS Vice President for research and full financial support. Conflict of Interest: None declared.
Interferon (IFN) is a cytokine broadly used to treat viral infections, malignancies, and disorders of the immune system. IFN is highly effective in the treatment of tumors that affect the vascular system, sellckchem including hypernephroma,1 hemangiomatosis2 and gastrointestinal tumors,3 in which significant vascularization develops. In the context of gastroenterology, the significance of IFN is mainly due to its prominent role in the treatment of chronic active hepatitis in patients infected with hepatitis C virus (HCV) and/or hepatitis B virus. IFN-based therapy is the cornerstone and one of the most effective treatment strategies for HCV infection.