Causes of mortality were as follows: HRS, 27 (7.8%), liver failure, 26 (7.5%); variceal bleeding, 13 (3.8%); sepsis, 9 (2.6%); others, 9 (2.6%). Survival time

was 36.7+/−1.5 months and 6- and 12-month survival rates were 86.7% and 80.8%, respectively. INR, bilirubin, albumin, glucose, creatinine, sodium, and CysC levels were significant factors on univariate analysis, while sodium and CysC levels and INR were independently associated factors with Nutlin-3a datasheet survival on multivariate analysis. INR (1.9+/−0.7 vs 1.4+/−0.4), bilirubin (9.0+/−9.0 mg/dL vs 3.7+/−4.5 mg/dL), albumin (2.7+/−0.4 g/dL vs 2.9+/−0.6 g/dL), creatinine (1.2+/−0.6 mg/dL vs 0.9+/−0.4 mg/dL), sodium (132.4+/−6.1 mEq/L vs 136.7+/−4.2 mEq/L), and CysC (1.5+/−0.6 mg/L vs 1.0+/−0.4 mg/L) levels were significantly

between patients with 1-year mortality and 1-year survivors. On binary logistic regression analysis, sodium and CysC levels and INR were independent predictors for 1-year mortality. The incidences of HRS at 6 and 12 months were 5.4% and 7.6%, respectively. Similarly, sodium and CysC levels and INR were independent factors for predicting development of HRS. Conclusions: Serum CysC level was a powerful indicator for mortality and development of HRS in patients with cirrhotic ascites. Disclosures: Anti-infection Compound high throughput screening Won Young Tak – Advisory Committees or Review Panels: Gilead Korea; Grant/ Research Support: SAMIL Pharma; Speaking and Teaching: Bayer Korea The following people have nothing to disclose: Yeon Seok Seo, Soo Young Park, Moon Young Kim, Sang Gyune Kim, Jun Yong Park, Hyung Joon Yim, Byoung

Kuk Jang, Seung Ha Park, Ji Hoon Kim, Ki Tae Suk, Jin Dong Kim, Tae Yeob Kim, June Sung Lee, Soung Won Jeong, Jae Young Jang, Hyonggin An, Soon Koo Baik, selleck products Jaeseok Hwang, Young Seok Kim, Joo Hyun Sohn, Soon Ho Um Electroencephalography (EEG) is useful to objectively diagnose/grade HE across its spectrum of severity. In addition, the EEG has recently been shown to improve the prognostic value of MELD. However, it requires expensive equipment, it is time-consuming, and hepatogastroenterologists are generally unfamiliar with its use/interpretation. Recent technological advances have lead to the development of low-cost, user-friendly EEG recording systems, allowing EEG acquisition in limited neurophysiological experience settings. The aim of this study was to assess the relationship between EEG parameters obtained from a Standard-EEG system and from a commercial, low-cost wireless headset (Light-EEG) in a group of well-characterized patients with cirrhosis. Forty patients with cirrhosis (32 males; 60±10 years) underwent EEG recording with both types of equipment, within 20 minutes. Standard spectral EEG parameters [i.e. Mean Dominant Frequency (MDF) and the relative power of the theta band (theta%)] were obtained from a bi-parietal derivation on both EEGs.