Blanchard TG, Czinn SJ, Correa P, Nakazawa T, Keelan M, Morningstar L, Santana-Cruz I, Maroo A, McCracken C, Shefchek K, Daugherty S, Song Y, Fraser CM, Fricke WF: Genome CHIR-99021 in vitro sequences of 65 Helicobacter pylori
see more strains isolated from asymptomatic individuals and patients with gastric cancer, peptic ulcer disease, or gastritis. Pathog Dis 2013, 68:39–43.PubMedCentralPubMedCrossRef 13. Xia HH, Talley NJ: Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis. Am J Gastroenterol 2001, 96:16–26.PubMedCrossRef 14. Galgani M, Busiello I, Censini S, Zappacosta S, Racioppi L, Zarrilli R: Helicobacter pylori induces apoptosis of human monocytes, but not monocyte-derived dendritic cells: role of the cag pathogenicity island. Infect Immun 2004, 72:4480–4485.PubMedCentralPubMedCrossRef 15. Radin JN, González-Rivera C, Ivie SE, McClain MS, Cover TL: Helicobacter pylori VacA induces programmed necrosis Selleckchem CDK inhibitor in gastric epithelial cells. Infect Immun 2011, 79:2535–2543.PubMedCentralPubMedCrossRef 16. Lee A, O’Rourke J, De Ungria MC, Robertson B, Daskalopoulos G, Dixon MF: A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology 1997, 112:1386–1397.PubMedCrossRef 17. Zhang S, Moss SF: Rodent models of Helicobacter infection, inflammation and disease. Methods Mol Biol 2012, 921:89–98.PubMedCentralPubMedCrossRef 18. Oertli M, Noben
M, Engler DB, Semper RP, Reuter S, Maxeiner J, Gerhard M, Taube C, Müller A: Helicobacter pylori γ-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence
and immune tolerance. Proc Natl Acad Sci U S A 2013, 110:3047–3052.PubMedCentralPubMedCrossRef 19. Steinert M, Leippe M, Roeder T: Surrogate host: protozoa and invertebrates for studying pathogen-host interactions. Int J Med Microbiol 2013, 293:321–332.CrossRef 20. Garcıà-Lara J, Needham AJ, Foster SJ: Invertebrates as animal models for Staphylococcus aureus pathogenesis: a window into host–pathogen interaction. FEMS Immunol Med Microbiol 2005, 43:311–323.PubMedCrossRef 21. Mylonakis E, Casadevall A, Ausubel FM: Exploiting amoeboid and nonvertebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog 2007, 3:e101.PubMedCentralPubMedCrossRef 22. Botham CM, Wandler Anidulafungin (LY303366) AM, Guillemin K: A transgenic Drosophila model demonstrates that the Helicobacter pylori CagA protein functions as a eukaryotic Gab adaptor. PLoS Pathog 2008, 4:e1000064.PubMedCentralPubMedCrossRef 23. Wandler AM, Guillemin K: Transgenic expression of the Helicobacter pylori virulence factor CagA promotes apoptosis or tumorigenesis through JNK activation in Drosophila. PLoS Pathog 2012, 8:e1002939.PubMedCentralPubMedCrossRef 24. Bergin D, Reeves EP, Renwick J, Wientjes FB, Kavanagh K: Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophils. Infect Immun 2005, 73:4161–4170.