Key Word(s): 1. Portal hypertensive gastropathy; 2. gastritis; 3. children; 4. varices Presenting Author: AI FUJIMOTO Additional Authors: OSAMU GOTO, YASUTOSHI OCHIAI, JYOICHIRO HORII, KOJI TAKAHASHI, KAORU TAKABAYASHI, MOTOKI SASAKI, RIEKO NAKAMURA, TOSHIHIRO NISHIZAWA, TADATERU MAEHATA, SEIJI SAGARA, SATOSHI KINOSHITA, TEPPEI AKIMOTO, TOSHIO URAOKA, NAOHISA YAHAGI Corresponding Author: AI FUJIMOTO Affiliations: Keio University, Keio University Hospital, Fukuyama Medical Center, Tokushima

Prefectural Central Hospital, Tokyo Medical Center, Keio University, Keio University, Keio University, Keio University,Keio University, Keio University, Keio University, Tokyo Medical Center, Keio University Objective: Indication of endoscopic submucosal MLN2238 research buy dissection (ESD) has

been expanding due to endoscopic technique and device improvement. Recently, we sometimes performed ESD for total pathological Alisertib in vitro diagnosis when preoperative diagnosis was unconfirmed. We examined treatment outcomes and adverse events of ESD in excluded indication criteria which were performed for total pathological diagnosis. Methods: We conducted a retrospective analysis for consecutive 28 early gastric cancers (EGC) in excluded indication criteria in 28 patients who were performed ESD between June 2010 and May 2014. We examined average of longer axis for lesions, procedure time, en bloc resection (ER) rate, en bloc complete resection with margin negative (ECR) rate, curative resection (CR) rate as treatment outcomes, and perforation rate, severe bleeding rate during ESD procedure, delayed bleeding rate, incidence of severe stenosis, incidence of severe aspiration pneumonia, incidence of disease-related death and emergency

surgery as adverse events. Results: The patients characteristics of 28 EGC in 28 patients were as follows: man : female 27:1, average age 68.5 ± 13.1. Treatment outcomes were as follows: average of longer axis for lesion 26.5 ± 13.2 mm, procedure time 75.7 ± 44.1 minutes, ER rate 28/28(100.0%), ECR rate 19/28(67.8%), CR rate 7/28(25.0%). Adverse Endocrinology antagonist events were as follows: perforation 1/28 (3.5%), delayed bleeding 2/28 (7.1%). there were no cases of severe bleeding during ESD procedure, severe stenosis, aspiration pneumonia, emergency surgery and disease-related death. Conclusion: ESD for total pathological diagnosis in excluded indication criteria has significance because ESD is safety and diagnosis of EGC has limitations. Key Word(s): 1. ESD included indication criteria Presenting Author: SHAHRIYAR GHAZANFAR Additional Authors: SAJIDA QURESHI, SAAD KHALID NIAZ Corresponding Author: SHAHRIYAR GHAZANFAR Affiliations: Dow University of Health Sciences, Dow University of Health Sciences Objective: To evaluate the success and complications of endoscopic balloon dilatation in patients with Achalasia Cardia, in a tertiary care setup.