Levofloxacin-resistant strains are increasing in Taiwan. “
“Helicobacter pylori (HP) eradication may reduce the risk of gastric cancer, and professional guidelines recommend eradication based on patients’ preference. However, little data exist regarding individual’s preference for HP eradication to prevent gastric Ensartinib molecular weight cancer. We explored healthy Korean populations’ preference for HP “screen and treat” strategy and its associated factors. We conducted a cross-sectional survey with 604 healthy adults expected to undergo screening esophagogastroduodenoscopy

during routine health checkups. Survey packages—including a decision aid about “screen and treat” strategy for the HP eradication—were sent to the eligible people NVP-BGJ398 clinical trial 1–3 weeks before the health checkup. Within the survey package, we first assessed people’s knowledge and experience with HP test and treatment, provided the decision aid, and evaluated participants’ preference for screening and treatment for HP to prevent gastric cancer. With the provision of the decision aid, most participants (73.7%) opted

for the “screen and treat” strategy. Having family member(s) with gastric cancer (adjusted odds ratio (aOR) = 2.28; 95% confidence interval (CI), 1.16–4.47), previous treatment history of HP (aOR = 2.70; 95% CI, 1.38–5.29), and higher baseline knowledge (aOR = 1.16; 95% CI, 1.07–1.26) were significantly associated with accepting the strategy. Most participants (71.4%)—and even individuals who did not choose “screen and treat” strategy—agreed with the provision with the decision aid. Individuals preferred to take the “screen and treat” strategy for the prevention of gastric cancer. Further intervention study is warranted to see if implementation of decisional support would improve decision medchemexpress quality and patient outcomes. “
“Background:  The most common complications of peptic

ulcer are bleeding and perforation. In many regions, definitive acid reduction surgery has given way to simple closure and Helicobacter pylori eradication. Aim:  To perform a systematic review and meta-analysis to ask whether this change in practice is in fact justified. Materials and Methods:  A search on the Cochrane Controlled Trials Register, Medline, and Embase was made for controlled trials of duodenal ulcer perforation patients using simple closure method plus postoperative H. pylori eradication therapy versus simple closure plus antisecretory non-eradication therapy. The long-term results for prevention of ulcer recurrence were compared. Results:  The pooled incidence of 1-year ulcer recurrence in H. pylori eradication group was 5.2% [95% confidence interval (CI) of 0.7 and 9.7], which is significantly lower than that of the control group (35.2%) with 95% CI of 0.25 and 0.45. The pooled relative risk was 0.15 with 95% CI of 0.06 and 0.